Abstract
Eutectic phenomenon has been investigated in binary system based on biopolymer hyaluronan (HN) and kojic acid dipalmitate (KAD). Solid-liquid phase diagram showed a significant dependence of melting points on weight fraction of KAD up to KAD < 0.5. A negligible regain to melting temperature of pure KAD occurred later. Simulations of molecular mechanics using a four-unit segment of HN and KAD revealed the interaction between carbonyl of KAD with 4-OH on N-acetylglucosamine unit of oligomer. Infrared vibrational spectroscopy also endorsed the existence of a weakly interacting system. Such behavior was expected due to steric hinderance and rigidity of biopolymer. The thermal decomposition temperature of HN (i.e., 215 °C) was increased to 322 °C in HK50 having HN and KAD in 1:50 w/w. Bioelectric impedance analysis revealed that these green materials could promote skin health in humans.
Recommended Citation
Shah, Syed Waqar Hussain; Imran, Sumbal; Bibi, Iram; Ali, Kashif; and Bashir, Nadia
(2024)
"Investigations of the Eutectic Formation and Skin Rejuvenation by Hyaluronan - Kojic Acid Dipalmitate System,"
Karbala International Journal of Modern Science: Vol. 10
:
Iss.
1
, Article 10.
Available at:
https://doi.org/10.33640/2405-609X.3344
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